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2016 (The 2nd) International Conference on Toxicological Alternatives & Translational Toxicology (The 1st Announcement)
‐ 2016-6-13    AuthorCST /


Sep 11th C 14th, 2016, Hangzhou, China

Background and Aims:
  Toxicity testing and risk assessment are critical for assurance of human health and environmental safety. Recently, toxicity testing is undergoing an unprecedented transformation from current low throughput, expensive, and lengthy in vivo testing with qualitative endpoints to human biology-based, high throughput and less expensive non-animal alternatives assays using robotic technologies with mechanistic quantitative parameters. Toxicological alternatives have become important tools in research and safety evaluation, and are increasingly applied in the risk assessment of chemicals, cosmetics, drugs, pesticides, et al. In particular after the release of the landmark report Toxicity Testing in the 21st Century: A Vision and a Strategy and development of adverse outcome pathway (AOP), significant achievements have been made in toxicological alternatives and translational toxicology. In order to promote the development and application of toxicity testing alternatives and translational toxicology in China, enhance the communications among national and international scientists from academia, corporations, and regulatory agencies, 2016 (The 2nd) International Conference on Toxicological Alternatives & Translational Toxicology will be held in Hangzhou, a beautiful city in southeast of China, during September 11th C 14th, 2016. A training program focusing on adverse outcome pathway and risk assessment will also be included in this conference. This workshop will provide a golden opportunity for national and international scientists to communicate and discuss up-to-date development and application of toxicological alternatives and translational toxicology, such as TT21C, AOP, new tools and technologies in alternatives and translational toxicology.
Venue: Hangzhou, China
Date: September 11th C 14th, 2016

Main topics include, not limited by:
Development and application of toxicological alternatives: 1) Development of non-animal alternatives; 2) Validation and regulatory acceptance of alternatives; 3) Application of alternatives in safety evaluation of cosmetics, environmental chemicals, and drugs.
Toxicity testing in the 21st century (TT21C) and risk assessment: 1) Chemical characterization (e.g. QSAR model); 2) Toxicity pathway description; 3) Toxicity dose-response assessment model; 4) In vivo-in vitro extrapolation (PBPK model); 5) RISK21.
Development and regulatory application of AOP: 1) Mode of action (MOA) and AOP; 2) Development and assessment of AOP (e.g. Weight of evidence analysis); 3) AOP program and case study; 4) Application of AOP in risk assessment of human health and environmental health.
Advance in translational toxicology: 1) Exposure science and assessment technology; 2) Toxicant exposure and diseases association study; 3) Toxicity testing new models (e.g. Stem cells, organs-on-chip)
AOP and risk assessment training program: 1) Definition of AOP and interpretation of guidance; 2) Development and assessment of AOP; 3) Case studies of AOP application in risk assessment; 4) Recent advance in AOP: challenge and opportunity.


September 11, 2016 Whole day: Registration, check-in
Afternoon: Committee meeting, The Society of Toxicity Testing and Alternative Methods, CEMS; The Society of Toxicological Alternatives and Translational Toxicology, CSOT
September 12, 2016 Opening ceremony
Plenary lectures
Invited presentations
September 13, 2016 Morning: Symposiums (Symposium I on Toxicological alternatives and Symposium II on Translational Toxicology) and poster session
Afternoon: Invited presentations, Closing ceremony
September 14, 2016 Morning: AOP and risk assessment training
Afternoon: University and/or company tourism in Hangzhou
September 15, 2016 Departure

Important date

December 30, 2015 Release of the first announcement (calling for abstract)
March 30, 2016 Release of the second announcement (Invited speakers and their topics will be announced)
Jun 30, 2016 Deadline for abstract collection
August 15, 2016 Confirmation of participation (online registration, registration fee payment, hotel reservation)
September 11, 2016 Check-in

Calling for Abstracts
Abstracts related to alternative and translational toxicology will be collected. Please submit your abstract via the meeting system at CSOT website (www.chntox.org). The deadline for abstract submission is on May 31st, 2015.


  Before August 15th, 2015 After August 15th, 2015
Member of CSOT, or CEMS 1500 RMB 1700 RMB
Graduate student 1100 RMB 1300 RMB
Normal delegate 1600 RMB 1800 RMB

800 RMB

Contact information
  If you have any inquires or comments, or need any assistance, please contact,
  Beijing: Dr. Xiaoyan Yuan (Tel: 010-66948463; Mobile: 13693191616)
  Hangzhou: Dr. Peihua Luo (Tel: 0571-88206915; Mobile: 13819140900)
  Fax: 010-63866617
  Email: tatt2015@163.com
  Website: for registration, abstract submission, and more information, please visit the website of Chinese SOT at www.chntox.org

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