Toxicology Research,01 March 2017, Issue 6, Page 107 to 264
链接：http://pubs.rsc.org/en/Journals/Journal/TX?issueID=TX006002

CONTENTS
Review Article (综述)

1.Progress of in vivo studies on the systemic toxicities induced by titanium dioxide nanoparticles
二氧化钛纳米颗粒诱导系统毒性的体内研究进展
Fashui Hong, Xiaohong Yu, Nan Wu and Yu-Qing Zhang
Toxicol. Res., 2017, 6, 115-133 DOI: 10.1039/C6TX00338A

Papers (论著)

1. Low toxicity and accumulation of zinc oxide nanoparticles in mice after 270-day consecutive dietary supplementation
270天连续膳食添加氧化锌纳米颗粒对小鼠产生低毒和蓄积作用
Jia-Hui Liu, Xin Ma, Yingying Xu, Huan Tang, Sheng-Tao Yang, Yi-Fan Yang, Dong-Dong Kang, Haifang Wang and Yuanfang Liu
Toxicol. Res., 2017, 6, 134-143 DOI: 10.1039/C6TX00370B

2. Cytotoxicity of T-2 and modified T-2 toxins: induction of JAK/STAT pathway in RAW264.7 cells by hepatopancreas and muscle extracts of shrimp fed with T-2 toxin
T-2和修饰性T-2毒素的细胞毒性： 喂食T-2毒素的虾的肝胰和肌肉提取物诱导RAW264.7细胞JAK/STAT通路激活
Xing Wang, Yaling Wang, Mei Qiu, Lijun Sun, Xiaobo Wang, Caihong Li, Defeng Xu and Ravi Gooneratne
Toxicol. Res., 2017, 6, 144-151 DOI: 10.1039/C6TX00392C

3. Evaluation of the DNA damaging potential of indigenous health hazardous quartz nanoparticles on the cultured lung cells
石英纳米颗粒对肺细胞的DNA损伤的固有健康危害评价
Sushma, Hridyesh Kumar, Iqbal Ahmad and Pradip Kumar Dutta  
Toxicol. Res., 2017, 6, 152-161  DOI: 10.1039/C6TX00414H 

4. Circulating miRNAs and their target genes associated with arsenism caused by coal-burning
与燃煤型砷中毒相关的循环miRNA及其靶基因
Baofei Sun, Junchao Xue, Jun Li, Fei Luo, Xiong Chen, Yonglian Liu, Qingling Wang, Caihua Qi, Zhonglan Zou, Aihua Zhang and Qizhan Liu
Toxicol. Res., 2017, 6, 162-172 DOI: 10.1039/C6TX00428H

5. The mutagenic mechanism of oxygenated alkylhydrazones occurs through alkyl radicals and alkyldiazonium ions
氧化烷基腙类通过烷基自由基和烷基重氮离子发挥致突变作用
Keiko Inami, Miki Takada, Miho Nagata, Toshinori Higashi and Masataka Mochizuki
Toxicol. Res., 2017, 6, 173-178 DOI: 10.1039/C6TX00430J

6. Chronic ciguatoxin poisoning causes emotional and cognitive dysfunctions in rats
雪卡毒素慢性中毒诱导大鼠情感及认知功能障碍
Jun Wang, Bing Cao, Xiangwei Yang, Jiajun Wu, Leo Lai Chan and Ying Li
Toxicol. Res., 2017, 6, 179-187 DOI: 10.1039/C5TX00475F

7. Evaluation of the toxicity and pathogenicity of biocontrol agents in murine models, chicken embryos and dermal irritation in rabbits
生物防治剂对小鼠、鸡胚和兔皮肤刺激的毒性和致病性评价
Ocampo-Suarez Iris Betsabee, Sanchez-Salas José Luis, Ragazzo-Sánchez Juan Arturo and Calderón-Santoyo Montserrat
Toxicol. Res., 2017, 6, 188-198 DOI: 10.1039/C6TX00275G

8. Cystamine attenuated behavioral deficiency via increasing the expression of BDNF and activating PI3K/Akt signaling in 2,5-hexanedione intoxicated rats
胱胺通过增强BDNF表达和激活PI3K/Akt信号通路减轻2.5-己二酮诱导的大鼠行为缺陷
Shuo Wang, Xianjie Li, Ming Li, Lulu Jiang, Hua Yuan, Wenting Han, Xujing Wang, Tao Zeng and Keqin Xie
Toxicol. Res., 2017, 6, 199-204 DOI: 10.1039/C6TX00409A

9. Exposure to few-layer graphene through diet induces oxidative stress and histological changes in the marine shrimp Litopenaeus vannamei
少层石墨烯饮食暴露诱导海虾（凡纳滨对虾）氧化应激和组织学改变
Amanda Lucena Fernandes, Marcelo Estrella Josende, Jefferson Patrício Nascimento, Adelina Pinheiro Santos, Sangram Keshai Sahoo, Flávio Manoel Rodrigues da Silva, Luis Alberto Romano, Clascídia Aparecida Furtado, Wilson Wasielesky, José Marìa Monserrat and Juliane Ventura-Lima
Toxicol. Res., 2017, 6, 205-214 DOI: 10.1039/C6TX00380J

10. Cigarette smoke extract induces the epithelial-to-mesenchymal transition via the PLTP/TGF-β1/Smad2 pathway in RLE-6TN cells
香烟烟雾提取物经由PLTP/TGF-β1/Smad2通路诱导RLE-6TN细胞的上皮间质转化
Hong Chen, Feng-ping Wu, Yong-zhen Yang, Xiu-ying Yu, Lu Zhang, Hui Zhang and Ya-juan Chen
Toxicol. Res., 2017, 6, 215-222 DOI: 10.1039/C6TX00378H

11. Endosulfan induces apoptosis by activating the negative regulation pathway of cell cycle and death receptor pathway in spermatogenic cells
硫丹通过激活细胞周期负性调控通路和死亡受体通路诱导生精细胞凋亡
Fang-Zi Guo, Ying Xu, Li-Hua Ren, Jin Zhang, Feng Zhang, Junchao Duan, Xian-Qing Zhou and Zhi-Wei Sun
Toxicol. Res., 2017, 6, 223-231 DOI: 10.1039/C6TX00315J

12. Paraquat disrupts the anti-inflammatory action of cortisol in human macrophages in vitro: therapeutic implications for paraquat intoxications
百草枯干扰皮质醇对体外人巨噬细胞的抗炎作用：对百草枯中毒治疗的启示
Gesiele Veríssimo, Aalt Bast and Antje R. Weseler
Toxicol. Res., 2017, 6, 232-241 DOI: 10.1039/C6TX00406G

13. Nano NiO induced liver toxicity via activating the NF-κB signaling pathway in rats
纳米NiO通过激活NF-κB信号通路介导大鼠的肝毒性
Fangfang Liu, Xuhong Chang, Minmin Tian, An Zhu, Lingyue Zou, Aijie Han, Li Su, Sheng Li and Yingbiao Sun
Toxicol. Res., 2017, 6, 242-250 DOI: 10.1039/C6TX00444J

14. Development of a BALB/c mouse model for food allergy: comparison of allergy-related responses to peanut agglutinin, β-lactoglobulin and potato acid phosphatase
食物过敏的BALB/c小鼠模型建立：花生凝集素、β-乳球蛋白和土豆酸性磷酸酶的过敏相关应答比较
Chen Chen, Lu Lianhua, Sun Nana, Li Yongning and Jia Xudong
Toxicol. Res., 2017, 6, 251-261 DOI: 10.1039/C6TX00371K