Toxicology Research, 01 July 2017, Issue 4, Page 383 to 562
链接：http://pubs.rsc.org/en/Journals/Journal/TX?issueID=TX006004


CONTENTS
Review Article (综述)
1. Toxic mechanisms of microcystins in mammals
微囊藻素对哺乳动物的毒性机制研究
Nicole L. McLellan and Richard A. Manderville
Toxicol. Res., 2017, 6, 391-405 DOI:10.1039/C7TX00043J

Communication (交流)
1. Circulating levels of miR-122 increase post-mortem, particularly following lethal dosing with pentobarbital sodium: implications for pre-clinical liver injury studies
循环miR-122水平在死后尤其在致死剂量戊巴比妥钠处理后显著增加：临床前肝损伤的预示
Joanna I. Clarke, Shiva Seyed Forootan, Jonathan D. Lea, Lawrence S. Howell, Josep Monne Rodriguez, Anja Kipar, Christopher E. Goldring, B. Kevin Park, Ian M. Copple and Daniel J. Antoine
Toxicol. Res., 2017,6, 406-411 DOI:10.1039/C6TX00442C

Papers (论著)
1. Mitochondria and MAPK cascades modulate endosulfan-induced germline apoptosis in Caenorhabditis elegans
线粒体和MAPK级联通路调节硫丹诱导的秀丽隐杆线虫的生殖细胞凋亡
Jingjing Wang, Hua Du, Yaguang Nie, Yun Wang, Hui Dai, Mudi Wang, Dayan Wang and An Xu Toxicol. Res., 2017,6, 412-419 DOI:10.1039/C7TX00046D

2. The muscarinic effect of anhydroecgonine methyl ester, a crack cocaine pyrolysis product, impairs melatonin synthesis in the rat pineal gland
强效可卡因热解产物脱水芽子碱甲酯的毒蕈碱样作用影响大鼠松果体的褪黑素生成
Xing Wang, Yaling Wang, Mei Qiu, Lijun Sun, Xiaobo Wang, Caihong Li, Defeng Xu and Ravi Gooneratne
Lívia Silva Medeiros de Mesquita, Raphael Caio Tamborelli Garcia, Fernanda Gaspar Amaral, Rafael Peres, Simone Miller Wood, RodrigoVincenzo de Luca Lucena, Eduardo Osório Frare, Mariana Vieira Abrahão, Tania Marcourakis, José Cipolla-Neto and Solange Castro Afeche
Toxicol. Res., 2017, 6, 420 DOI:10.1039/C7TX00009J

3. Coal combustion related fine particulate matter (PM2.5) induces toxicity in Caenorhabditis elegans by dysregulating microRNA expression
microRNA表达失调介导燃煤相关细颗粒物（PM2.5）诱导的秀丽隐杆线虫毒性
Qiuli Wu, Xiaoxiao Han, Di Wang, Fang Zhao and Dayong Wang
Toxicol. Res., 2017, 6, 432 DOI:10.1039/C7TX00107J 

4. Mucor circinelloides: efficiency of bioremediation response to heavy metal pollution
卷枝毛霉对重金属污染的生物降解效率
Xu Zhang, Huanhuan Yang and Zhaojie Cui
Toxicol. Res., 2017, 6, 442 DOI:10.1039/C7TX00110J

5. Regulating temperature and relative humidity in air–liquid interface in vitro systems eliminates cytotoxicity resulting from control air exposures
调节气液界面系统温度及相对湿度可消除对照空气暴露介导的细胞毒性
Jose Zavala, Rebecca Greenan, Q. Todd Krantz, David M. DeMarini, Mark Higuchi, M. Ian Gilmour and Paul A. White
Toxicol. Res., 2017, 6, 448 DOI:10.1039/C7TX00109F

6. A developmental toxicity assay of Carpesii Fructus on zebrafish embryos/larvae
鹤虱对斑马鱼胚胎及幼鱼的发育毒性试验
Qing Xia, Jun Luo, Xue Mei, Yutong Wang, Wanzhen Huang, Jinfeng Wang, Ranran Yang, Zhiqiang Ma and Ruichao Lin
Toxicol. Res., 2017, 6, 460 DOI:10.1039/C7TX00005G

7. ATF2 partly mediated the expressions of proliferative factors and inhibited pro-inflammatory factors’ secretion in arsenite-treated human uroepithelial cells
ATF2部分介导调控砷暴露致人尿道上皮细胞的增殖因子表达并抑制前炎性因子分泌
Shengnan Liu, Fei Wang, Jieyu Liu, Peiyu Jin, Xiaoyan Wang, Li Yang and Shuhua Xi
Toxicol. Res., 2017, 6, 468 DOI:10.1039/C6TX00407E

8. Differential gene responses in the embryo of the green mussel Perna viridis exposed to dichlorodiphenyltrichloroethane (DDT)
二氯二苯三氯乙烷（DDT）暴露诱导的翡翠贻贝胚胎差异基因应答
Xiu Jiang, Tianle Tang, Hongwei Zhao, Qinqin Song, Hailong Zhou, Qian Han and Xiaoping Diao
Toxicol. Res., 2017, 6, 477 DOI:10.1039/C7TX00087A

9. Biosafety study and mechanism comparison on two types of silica with different nanostructures
两种不同硅纳米材料的生物安全性及机制比较
Yang Zhang, Xianhui Chen, Bo Zhao, Hounan Wu, Lan Yuan, Hua Zhang, Wenbing Dai, Bing He, Gengmei Xing, Qiang Zhang and Xueqing Wang
Toxicol. Res., 2017, 6, 487 DOI:10.1039/C7TX00076F

10. Zinc is a determinant of the cytotoxicity of Ziram, a dithiocarbamate fungicide, in rat thymic lymphocytes: possible environmental risks
锌是二硫代氨基甲酸酯类杀菌剂福美锌诱导大鼠淋巴细胞毒性的决定因素：潜在的环境风险
Yumiko Kanemoto-Kataoka, Tomohiro M. Oyama, Hitoshi Ishibashi and Yasuo Oyama
Toxicol. Res., 2017, 6, 499 DOI:10.1039/C7TX00052A

11. Potential effects of low molecular weight phthalate esters (C16H22O4 and C12H14O4) on the freshwater fish Cyprinus carpio
低分子量邻苯二甲酸酯(C16H22O4 和C12H14O4)对淡水鲤鱼的潜在作用
R. K. Poopal, M. Ramesh, V. Maruthappan and R. Babu Rajendran
Toxicol. Res., 2017, 6, 505 DOI:10.1039/C7TX00084G

12. Protective effects of coenzyme Q10 and resveratrol on oxidative stress induced by various dioxins on transheterozigot larvae of Drosophila melanogaster
辅酶Q10和白藜芦醇对多种二恶英诱导果蝇幼虫氧化应激的保护作用
Deniz Altun Çolak and Handan Uysal
Toxicol. Res., 2017, 6, 521 DOI:10.1039/C7TX00027H

13. Eugenia uniflora leaf essential oil promotes mitochondrial dysfunction in Drosophila melanogaster through the inhibition of oxidative phosphorylation
红果仔叶精油通过抑制氧化磷酸化致果蝇线粒体功能紊乱
Nélson R. de Carvalho, Nathane R. Rodrigues, Giulianna E. Macedo, Ivi J. Bristot, Aline A. Boligon, Marli M. de Campos, Francisco A. B. Cunha, Henrique D. Coutinho, Fabio Klamt, Thomas J. S. Merritt, Thaís Posser and Jeferson L. Franco
Toxicol. Res., 2017, 6, 526 DOI:10.1039/C7TX00072C

14. Toxicological effects of graphene oxide on Saccharomyces cerevisiae
氧化石墨烯对酿酒酵母的毒理作用
Song Zhu, Fei Luo, Bin Zhu and Gao-Xue Wang
Toxicol. Res., 2017, 6, 535 DOI:10.1039/C7TX00103G

15. A comparison of toxicity and toxicokinetics in rats and dogs following twenty-eight-day, repeat-dose oral administration of nifurtimox
硝呋莫司28天经口重复剂量染毒对大鼠和犬的毒性和毒代动力学比较
Ye Li, Tian-tian Liu, Hong-tao Jin, Piao-piao Zhang, Dan Qin, Qian-qian Zhang, Wen-tao Wu, Cui-ping Yang and Ai-ping Wang
Toxicol. Res., 2017, 6, 544 DOI:10.1039/C7TX00061H

16. A comparative study of hydrophilic phosphine hexanuclear rhenium cluster complexes’ toxicity
亲水膦六核铼簇复合物的毒性比较研究
Anna A. Krasilnikova, Anastasiya O. Solovieva, Anton A. Ivanov, Konstantin A. Brylev, Tatiana N. Pozmogova, Marina A. Gulyaeva, Olga G. Kurskaya, Alexander Y. Alekseev, Alexander M. Shestopalov, Lidiya V. Shestopalova, Alexander F. Poveshchenko, Olga A. Efremova, Yuri V. Mironov and Michael A. Shestopalov
Toxicol. Res., 2017, 6, 554 DOI:10.1039/C7TX00083A