Toxicology Research, 01 November 2017, Issue 6, Page 731 to 970
链接：http://pubs.rsc.org/en/Journals/Journal/TX?issueID=TX006006

CONTENTS（内容）

Review Article (综述)
1. Genotoxicity of ortho-quinones: reactive oxygen species versus covalent modification
邻醌的遗传毒性：活性氧和共价修饰对比
Trevor M. Penning
Toxicol. Res., 2017, 6, 740 DOI:10.1039/C7TX00223H

2. The ABCs of pesticide toxicology: amounts, biology, and chemistry
农药毒理学的ABC：用量(A)，生物学 (B) 及化学 (C) 特性
John E. Casida and Robert J. Bryant
Toxicol. Res., 2017, 6, 755 DOI:10.1039/C7TX00198C

3. Toxicological effects of patulin mycotoxin on the mammalian system: an overview
棒曲霉素对哺乳动物系统的毒性效应总结
Saurabh Pal, Neha Singh and Kausar Mahmood Ansari
Toxicol. Res., 2017, 6, 764 DOI:10.1039/C7TX00138J

4. Modulation of estrogen synthesis and metabolism by phytoestrogens in vitro and the implications for women's health
植物雌激素对体外雌激素合成和代谢的调节及对女性健康的启示
Majorie B. M. van Duursen
Toxicol. Res., 2017, 6, 772 DOI:10.1039/C7TX00184C

Papers (论著)
1. Candidate genes responsible for early key events of phenobarbital-promoted mouse hepatocellular tumorigenesis based on differentiation of regulating genes between wild type mice and humanized chimeric mice
基于野生型及人源嵌合小鼠调节基因改变筛选苯巴比妥致小鼠肝细胞肿瘤发生的早期关键事件相关基因
Ayako Ohara, Yasuhiko Takahashi, Miwa Kondo, Yu Okuda, Shuji Takeda, Masahiko Kushida, Kentaro Kobayashi, Kayo Sumida and Tomoya Yamada
Toxicol. Res., 2017, 6, 795 DOI:10.1039/C7TX00163K

2. Cell to rodent: toxicological profiling of folate grafted thiomer enveloped nanoliposomes
从细胞到啮齿类动物：叶酸聚合物包被纳米脂质体的毒性特征
Muhammad Farhan Sohail, Hafiz Shoaib Sarwar, Ibrahim Javed, Akhtar Nadhman, Syed Zajif Hussain, Hamid Saeed, Abida Raza, Nadeem Irfan Bukhari, Irshad Hussain and Gul Shahnaz
Toxicol. Res., 2017, 6, 814 DOI:10.1039/C7TX00146K

3. Toxicity of Pb2+ on rat liver mitochondria induced by oxidative stress and mitochondrial permeability transition
Pb2+通过氧化应激和线粒体通透性转换诱导大鼠肝脏线粒体毒性
Long Ma, Jun-Yi Liu, Jia-Xin Dong, Qi Xiao, Jie Zhao and Feng-Lei Jiang
Toxicol. Res., 2017, 6, 822 DOI:10.1039/C7TX00204A

4. In silico prediction of pesticide aquatic toxicity with chemical category approaches
利用化学分类法及计算机模拟预测农药的水生毒性
Fuxing Li, Defang Fan, Hao Wang, Hongbin Yang, Weihua Li, Yun Tang and Guixia Liu
Toxicol. Res., 2017, 6, 831 DOI:10.1039/C7TX00144D

5. Metabolomics for the early detection of cisplatin-induced nephrotoxicity
运用代谢组学法早期检测顺铂诱导的肾脏毒性
Takeshi Ezaki, Shin Nishiumi, Takeshi Azuma and Masaru Yoshida
Toxicol. Res., 2017, 6, 843 DOI:10.1039/C7TX00171A

6. Strategy of metal iron doping and green-mediated ZnO nanoparticles: dissolubility, antibacterial and cytotoxic traits
掺铁离子和植物提取物合成的ZnO纳米颗粒的策略：可溶性、抗菌活性和细胞毒性特征评价
S. Aiswarya Devi, M. Harshiny, S. Udaykumar, P. Gopinath and M. Matheswaran
Toxicol. Res., 2017, 6, 854 DOI:10.1039/C7TX00093F

7. Effect of deoxynivalenol on apoptosis, barrier function, and expression levels of genes involved in nutrient transport, mitochondrial biogenesis and function in IPEC-J2 cells
脱氧雪腐镰刀菌烯醇对IPEC-J2细胞凋亡、屏障功能及相关基因表达的作用参与调控营养运输和线粒体的生物合成及功能
Peng Liao, Meifang Liao, Ling Li, Bie Tan and Yulong Yin
Toxicol. Res., 2017, 6, 866 DOI:10.1039/C7TX00202E

8. MicroRNA-29b inhibits supernatants from silica-treated macrophages from inducing extracellular matrix synthesis in lung fibroblasts
MicroRNA-29b 抑制二氧化硅处理巨噬细胞培养上清诱导的肺成纤维细胞细胞外基质合成
Ximeng Lian, Xiaowei Chen, Jingping Sun, Guoliang An, Xiaoli Li, Yan Wang, Piye Niu, Zhonghui Zhu and Lin Tian
Toxicol. Res., 2017, 6, 878 DOI:10.1039/C7TX00126F

9. Nanoparticulate titanium dioxide-inhibited dendritic development is involved in apoptosis and autophagy of hippocampal neurons in offspring mice
二氧化钛纳米颗粒抑制树突发育参与子鼠海马神经元细胞的凋亡和自噬
Yingjun Zhou, Fashui Hong, Yusheng Tian, Xiangyu Zhao, Jie Hong, Yuguan Ze and Ling Wang
Toxicol. Res., 2017, 6, 889 DOI:10.1039/C7TX00153C

10. Tributylphosphate (TBP) and tris (2-butoxyethyl) phosphate (TBEP) induced apoptosis and cell cycle arrest in HepG2 cells
磷酸三丁酯(TBP)和磷酸三（2-丁氧基乙）酯(TBEP)诱导HepG2细胞凋亡及细胞周期阻滞
Guofa Ren, Jingwen Hu, Yu Shang, Yufang Zhong, Zhiqiang Yu and Jing An
Toxicol. Res., 2017, 6, 902 DOI:10.1039/C7TX00180K

11. Early afterdepolarisation tendency as a simulated pro-arrhythmic risk indicator
早期后除极倾向可作为模拟心律失常的风险提示
Beth McMillan, David J. Gavaghan and Gary R. Mirams
Toxicol. Res., 2017, 6, 912 DOI:10.1039/C7TX00141J

12. Diverse cellular actions of tert-butylhydroquinone, a food additive, on rat thymocytes
食物添加剂叔丁基对苯二酚对大鼠胸腺细胞的多重作用
Norio Kamemura, Keisuke Oyama, Kaori Kanemaru, Kumio Yokoigawa and Yasuo Oyama
Toxicol. Res., 2017, 6, 922 DOI:10.1039/C7TX00183E

13. Comparative effects of a candidate modified-risk tobacco product Aerosol and cigarette smoke on human organotypic small airway cultures: a systems toxicology approach
运用系统毒理学方法比较减毒烟草产品气溶胶与香烟烟雾在人小气道器官培养模型的毒作用
Anita R. Iskandar, Yannick Martinez, Florian Martin, Walter K. Schlage, Patrice Leroy, Alain Sewer, Laura Ortega Torres, Shoaib Majeed, Celine Merg, Keyur Trivedi, Emmanuel Guedj, Stefan Frentzel, Carole Mathis, Nikolai V. Ivanov, Manuel C. Peitsch and Julia Hoeng
Toxicol. Res., 2017, 6, 930 DOI:10.1039/C7TX00152E

14. Luminescent CdSe@ZnS nanocrystals embedded in liposomes: a cytotoxicity study in HeLa cells
荧光CdSe@ZnS纳米晶体嵌入脂质体对HeLa细胞的毒性研究
Vincenzo De Leo, Francesco Milano, Aurora Paiano, Roberta Bramato, Livia Giotta, Roberto Comparelli, Silvia Ruscigno, Angela Agostiano, Cecilia Bucci and Lucia Catucci
Toxicol. Res., 2017, 6, 947 DOI:10.1039/C7TX00172J

15. Evaluation of the toxicity of iron-ion irradiation in murine bone marrow dendritic cells via increasing the expression of indoleamine 2,3-dioxygenase 1
铁离子辐射毒性评价：通过上调吲哚胺2,3-双加氧酶1表达诱导小鼠骨髓树突状细胞毒性
Yi Xie, Jun-Fang Yan, Jing-Yi Ma, Hong-Yan Li, Yan-Cheng Ye, Yan-Shan Zhang and Hong Zhang
Toxicol. Res., 2017, 6, 958 DOI:10.1039/C7TX00194K