Toxicology Research, 01 July 2018, Issue 4, Page 541 to 720
链接：http://pubs.rsc.org/en/Journals/Journal/TX?issueID=TX007004


CONTENTS

Editorial (述评)
1. Appreciation of Iain Purchase and Cliff Elcombe
Lewis Smith
Toxicol. Res., 2018, 7, 548 DOI:10.1039/C8TX90008F

Review Articles (综述)
1. The failure of rodent carcinogenesis as a model for Man
啮齿类动物用作人类致癌模型的失败
Colin Berry
Toxicol. Res., 2018, 7, 553 DOI:10.1039/C7TX00283A

2. Goodbye to the bioassay
和动物致癌试验说再见
Jay I. Goodman
Toxicol. Res., 2018, 7, 558 DOI:10.1039/C8TX00004B

Papers (论著)
1. Screening for human urinary bladder carcinogens: two-year bioassay is unnecessary
人类膀胱癌致癌物筛查：两年期动物致癌试验并非必要
Samuel M. Cohen
Toxicol. Res., 2018, 7, 565 DOI:10.1039/C7TX00294G

Review Articles (综述)
1. Collaboration and competition: ethics in toxicology
合作与竞争：毒理学研究的伦理学问题
Emma S. Walker and Ruth A. Roberts
Toxicol. Res., 2018, 7, 576 DOI:10.1039/C7TX00306D

2. Skin and respiratory chemical allergy: confluence and divergence in a hybrid adverse outcome pathway
皮肤与呼吸道化合性过敏：混合有害结局路径(AOP)中的共性与分歧
Ian Kimber, Alan Poole and David A. Basketter
Toxicol. Res., 2018, 7, 586 DOI:10.1039/C7TX00272F

3. Chromatin dynamics underlying latent responses to xenobiotics
染色质动力学研究揭示对外源化合物的潜在应答
Jonathan Moggs and Rémi Terranova
Toxicol. Res., 2018, 7, 606 DOI:10.1039/C7TX00317J

4. The safety evaluation of food flavouring substances: the role of metabolic studies
食品调味剂的安全性评价：代谢研究的作用
Robert L. Smith, Samuel M. Cohen, Shoji Fukushima, Nigel J. Gooderham, Stephen S. Hecht, F. Peter Guengerich, Ivonne M. C. M. Rietjens, Maria Bastaki, Christie L. Harman, Margaret M. McGowen and Sean V. Taylor
Toxicol. Res., 2018, 7, 618 DOI:10.1039/C7TX00254H

5. The association between chemical-induced porphyria and hepatic cancer
化合物诱导的卟啉病与肝癌的关系
Andrew G. Smith and John R. Foster
Toxicol. Res., 2018, 7, 647 DOI:10.1039/C8TX00019K

6. Role of xenobiotics in the induction and progression of fatty liver disease
外源化学物在脂肪肝启动与进展阶段的作用
James E. Klaunig, Xilin Li and Zemin Wang
Toxicol. Res., 2018, 7, 664 DOI:10.1039/C7TX00326A

7. Case examples of an evaluation of the human relevance of the pyrethroids/pyrethrins-induced liver tumours in rodents based on the mode of action
除虫菊酯/除虫菊素诱导啮齿类动物肝脏肿瘤的毒作用模式与人类相关性评价的案例研究
Tomoya Yamada
Toxicol. Res., 2018, 7, 681 DOI:10.1039/C7TX00288B

8. Human relevance of rodent liver tumour formation by constitutive androstane receptor (CAR) activators
合成的雄甾烷受体(CAR)激活剂诱导啮齿类动物肝脏肿瘤生成的人类相关性的研究
Brian G. Lake
Toxicol. Res., 2018, 7, 697 DOI:10.1039/C8TX00008E