Toxicology Research, 01 May 2016, Issue 3, Page 721 to 976
链接：http://pubs.rsc.org/en/journals/journalissues/tx#!issueid=tx005003

CONTENTS
Review Article (综述)
1. The effects of T-2 toxin on the prevalence and development of Kashin–Beck disease in China: a meta-analysis and systematic review
T-2毒素对中国大骨节病流行发展影响的meta分析和系统综述
Danyang Li, Jing Han, Xiong Guo, Chengjuan Qu, Fangfang Yu and Xiaofang Wu
Toxicol. Res., 2016, 5, 731-751 DOI: 10.1039/C5TX00377F

Papers (论著)
1. Formaldehyde-induced toxicity in the nasal epithelia of workers of a plastic laminate plant
甲醛对层压塑料厂工人鼻腔上皮的毒性作用
Roberto Bono, Armelle Munnia, Valeria Romanazzi, Valeria Bellisario, Filippo Cellai and Marco E. M. Peluso
Toxicol. Res., 2016, 5, 752-760 DOI: 10.1039/C5TX00478K
2. eIF3 regulates migration, invasion and apoptosis in cadmium transformed 16HBE cells and is a novel biomarker of cadmium exposure in a rat model and in workers
eIF3调节镉诱导的16HBE转化细胞的迁移、侵袭和凋亡并可作为大鼠和工人镉暴露的新型生物标志物
Zhiheng Zhou, Qian Lu, Qinhai Huang, Chanjiao Zheng, Baoxin Chen and Yixiong Lei
Toxicol. Res., 2016, 5, 761-772 DOI: 10.1039/C5TX00250H
3. In silico prediction of the developmental toxicity of diverse organic chemicals in rodents for regulatory purposes
计算机预测应用于多种有机化学物致啮齿类动物发育毒性的风险管理
Nikita Basant, Shikha Gupta and Kunwar P. Singh
Toxicol. Res., 2016, 5, 773-787 DOI: 10.1039/C5TX00493D
4. Induction and inhibition of human cytochrome P4501 by oxygenated polycyclic aromatic hydrocarbons
氧化态多环芳烃对人细胞色素酶P4501的诱导与抑制作用
Emma Wincent, Florane Le Bihanic and Kristian Dreij
Toxicol. Res., 2016, 5, 788-799 DOI: 10.1039/C6TX00004E
5. STAT3 methylation in white blood cells as a novel sensitive biomarker for the toxic effect of low-dose benzene exposure
白细胞STAT3基因甲基化可作为低剂量苯暴露毒性效应的新型敏感生物标志物
Di Liu, Yujiao Chen, Pengling Sun, Wenlin Bai and Ai Gao
Toxicol. Res., 2016, 5, 800-807 DOI: 10.1039/C5TX00445D
6. The influence of the SULT1A status – wild-type, knockout or humanized – on the DNA adduct formation by methyleugenol in extrahepatic tissues of mice
野生型、敲除或人源SULT1A对甲基丁香酚诱导肝外组织DNA加合物生成的作用
K. Herrmann, W. Engst, S. Florian, A. Lampen, W. Meinl and H. R. Glatt
Toxicol. Res., 2016, 5, 808-815 DOI: 10.1039/C5TX00358J
7. Bronchial epithelial innate and adaptive immunity signals are induced by polycyclic aromatic hydrocarbons
多环芳烃诱导支气管上皮固有和获得性免疫信号
Kirsty Meldrum, Timothy W. Gant, Sameirah Macchiarulo and Martin O. Leonard
Toxicol. Res., 2016, 5, 816-827 DOI: 10.1039/C5TX00389J
8. Perinatal exposure to low-dose bisphenol A disrupts learning/memory and DNA methylation of estrogen receptor alpha in the hippocampus
围产期低剂量双酚A暴露干扰学习记忆和海马雌激素受体α的DNA甲基化
Huailong Chang, Mu Wang, Wei Xia, Tian Chen, Wenqian Huo, Zhenxing Mao, Yingshuang Zhu, Yuanyuan Li and Shunqing Xu
Toxicol. Res., 2016, 5, 828-835 DOI: 10.1039/C5TX00449G
9. Absence of cytotoxicity towards microglia of iron oxide (α-Fe2O3) nanorhombohedra
氧化铁(α-Fe2O3)纳米菱面体对小胶质细胞无毒性作用
Crystal S. Lewis, Luisa Torres, Jeremy T. Miyauchi, Cyrus Rastegar, Jonathan M. Patete, Jacqueline M. Smith, Stanislaus S. Wong and Stella E. Tsirka
Toxicol. Res., 2016, 5, 836-847 DOI: 10.1039/C5TX00421G
10. MiR-146a affects the alteration in myeloid differentiation induced by hydroquinone in human CD34+ hematopoietic progenitor cells and HL-60 cells
MiR-146a影响氢醌诱导的人CD34+造血祖细胞和HL-60细胞的髓系分化
Weixin Yuan, Qing Sun, Yanping Jiang, Xinjie Zhang, Liping Chen, Chunjiao Xie, Fei Qin, Yuncong Chen, Hongxin Lv, Wen Chen and Yongmei Xiao
Toxicol. Res., 2016, 5, 848-858 DOI: 10.1039/C5TX00419E
11. Valproic acid causes radiosensitivity of breast cancer cells via disrupting the DNA repair pathway
丙戊酸通过干扰DNA修复通路增加乳腺癌细胞的辐射敏感性
Yue Luo, Hui Wang, Xipeng Zhao, Chao Dong, Fengmei Zhang, Gang Guo, Gongshe Guo, Xiaowei Wang, Simon N. Powell and Zhihui Feng
Toxicol. Res., 2016, 5, 859-870 DOI: 10.1039/C5TX00476D
12. Autophagy and autophagy dysfunction contribute to apoptosis in HepG2 cells exposed to nanosilica
自噬功能紊乱促进纳米二氧化硅诱导的HepG2细胞凋亡
Yongbo Yu, Junchao Duan, Yang Yu, Yang Li, Yang Zou, Yumei Yang, Lizhen Jiang, Qiuling Li and Zhiwei Sun
Toxicol. Res., 2016, 5, 871-882 DOI: 10.1039/C5TX00465A
13. Improving the prediction of organism-level toxicity through integration of chemical, protein target and cytotoxicity qHTS data
整合化学物、靶蛋白及细胞毒性的qHTS数据提升系统毒性的预测能力
Chad H. G. Allen, Alexios Koutsoukas, Isidro Cortés-Ciriano, Daniel S. Murrell, Thérèse E. Malliavin, Robert C. Glen and Andreas Bender
Toxicol. Res., 2016, 5, 883-894 DOI: 10.1039/C5TX00406C
14. Cigarette smoke compounds induce cellular redox imbalance, activate NF-κB, and increase TNF-α/CRP secretion: a possible pathway in the pathogenesis of COPD
香烟烟雾中化合物诱导细胞氧化还原失衡、激活NF-κB并增加 TNF-α/CRP分泌：COPD发病的可能通路
Tapan Dey, Prachurjya Dutta, Prasenjit Manna, Jatin Kalita, Hari Prasanna Deka Boruah, Alak Kumar Buragohain, Balagopalan Unni, Dibyajyoti Ozah, Mihir Kumar Goswami and Ratan Kumar Kotokey
Toxicol. Res., 2016, 5, 895-904 DOI: 10.1039/C5TX00477B
15.Acetaminophen-induced S-nitrosylation and S-sulfenylation signalling in 3D cultured hepatocarcinoma cell spheroids
对乙酰氨基酚诱导3D培养肝癌细胞球的S-亚硝基化和S-亚磺酰化信号通路
Qian Zhang, Wei Liu, Qiao Niu, Yu Wang, Huimin Zhao, Huifang Zhang, Jing Song, Shuji Tsuda and Norimitsu Saito
Toxicol. Res., 2016, 5, 539-546 DOI: 10.1039/C5TX00184F
16. Effects of tris(1,3-dichloro-2-propyl)phosphate on pathomorphology and gene/protein expression related to thyroid disruption in rats
三(1,3-二氯-2-丙基)磷酸(TDCIPP)对大鼠甲状腺病理形态和功能失调相关基因/蛋白表达的作用
Fei Zhao, Jing Wang, Yanjun Fang, Jia Ding, Honglian Yang, Li Li, Zhuge Xi and Haixuan Qiao Toxicol. Res., 2016, 5, 921-930 DOI: 10.1039/C5TX00374A
17. Bone morphogenetic protein-7 prevented epithelial-mesenchymal transition in RLE-6TN cells
骨形态生成蛋白-7抑制RLE-6TN细胞的上皮间质转化
Yan Wang, Di Liang, Zhonghui Zhu, Xiaoli Li, Guoliang An, Piye Niu, Li Chen and Lin Tian Toxicol. Res., 2016, 5, 931-937 DOI: 10.1039/C5TX00471C
18. Pancreatic damage induced by cigarette smoke: the specific pathological effects of cigarette smoke in the rat model
香烟烟雾暴露大鼠模型中特定胰腺病理损伤
Senay Topsakal, Ozlem Ozmen, Rahime Aslankoc and Demet Hancer Aydemir
Toxicol. Res., 2016, 5, 938-945 DOI: 10.1039/C5TX00496A
19. Fine particulate matter induces vascular endothelial activation via IL-6 dependent JAK1/STAT3 signaling pathway
细颗粒物通过IL-6依赖的JAK1/STAT3信号通路诱导血管内皮激活
Hejing Hu, Jing Wu, Qiuling Li, Collins Asweto, Lin Feng, Xiaozhe Yang, Fengkui Duan, Junchao Duan and Zhiwei Sun
Toxicol. Res., 2016, 5, 946-953 DOI: 10.1039/C5TX00351B
20. Diallyl trisulfide protects the liver against hepatotoxicity induced by isoniazid and rifampin in mice by reducing oxidative stress and activating Kupffer cells
二烯丙基三硫通过减少氧化应激并激活库普弗细胞以保护肝脏免于异烟肼和利福平诱导的小鼠肝毒性
Yilin Yang, Lulu Jiang, Shuo Wang, Tao Zeng and Keqin Xie
Toxicol. Res., 2016, 5, 954-962 DOI: 10.1039/C5TX00440C
21. Induction of protective autophagy against apoptosis in HepG2 cells by isoniazid independent of the p38 signaling pathway
异烟肼依赖的p38信号通路诱导HepG2细胞保护性自噬以拮抗凋亡
Tian-Guang Zhang, Yi-Mei Wang, Jun Zhao, Ming-Yu Xia, Shuang-Qing Peng and Takashi Ikejima
Toxicol. Res., 2016, 5, 963-972 DOI: 10.1039/C5TX00470E