Toxicology Research,01 September 2016, Issue 5, Page 1259 to 1492
链接：http://pubs.rsc.org/en/Journals/Journal/TX?issueID=TX005005
　

CONTENTS

Communications (交流)
1.Cysteine-induced hormesis effect of silver nanoparticles
半胱氨酸诱导银纳米颗粒的毒物兴奋性效应
Zhi Guo, Guiqiu Chen, Guangming Zeng, Zhenzhen Huang, Anwei Chen, Liang Hu, Jiajia Wang and Longbo Jiang
Toxicol. Res., 2016, 5, 1268-1272 DOI: 10.1039/C6TX00222

Papers (论著)
1.Gender specific differences in the liver proteome of rats exposed to short term and low-concentration hexabromocyclododecane (HBCD)
短期低浓度六溴环十二烷(HBCD)暴露对大鼠肝蛋白质组的性别差异研究
I. Miller, C. Diepenbroek, E. Rijntjes, J. Renaut, K. J. Teerds, C. Kwadijk, S. Cambier, A. J. Murk, A. C. Gutleb and T. Serchi
Toxicol. Res., 2016, 5, 1273-1283 DOI: 10.1039/C6TX00166A

2.Long-term exposure of K562 cells to benzene metabolites inhibited erythroid differentiation and elevated methylation in erythroid specific genes
苯代谢产物长期暴露抑制K562细胞红系分化并导致特定红系基因的高甲基化
K. Y. Tang, C. H. Yu, L. Jiang, M. Gong, W. J. Liu, Y. Wang, N. X. Cui, W. Song, Y. Sun and Z. C. Yi
Toxicol. Res., 2016, 5, 1284-1297 DOI: 10.1039/C6TX00143B

3.Comparative oxidative stress elicited by nanosilver in stable HSPA1A promoter-driven luciferase reporter HepG2 and A549 cells
应用HSPA1A启动子荧光素酶报告系统比较银纳米颗粒在HepG2和A549细胞的氧化应激
Aleksey A. Pivtsaev and Valeriy I. Razov
Toxicol. Res., 2016, 5, 1306-1308 DOI: 10.1039/C6TX00147E

4.Detection of the carcinogenic properties of synthetic and natural dyes using positron annihilation lifetime spectrometry
正电子湮没寿命谱检测合成和天然染料的致癌特性
Anu Pal, Shamshad Alam, Lalit K. S. Chauhan, Prem N. Saxena, Mahadeo Kumar, Ghazi N. Ansari, Dhirendra Singh and Kausar M. Ansari
Toxicol. Res., 2016, 5, 1066-1077 DOI: 10.1039/C6TX00026F

5.Combined toxicity of Fe3O4 nanoparticles and cadmium chloride in mice
Fe3O4纳米颗粒和氯化镉对小鼠的联合毒性
Yan Zhang, Xiaolong Xu, Shanshan Zhu, Jiajia Song, Xincheng Yan and Shang Gao
Toxicol. Res., 2016, 5, 1309-1317 DOI: 10.1039/C6TX00190

6.Effects of prenatal and lactation nicotine exposure on glucose homeostasis, lipogenesis and lipid metabolic profiles in mothers and offspring
尼古丁孕期和哺乳期暴露对母亲及子代血糖稳态、脂质生成和脂质代谢谱的影响
Jie Fan, Jie Ping, Jie Xiang, Yi-song Rao, Wan-xia Zhang, Ting Chen, Li Zhang and You-e Yan
Toxicol. Res., 2016, 5, 1318-1328 DOI: 10.1039/C6TX00237D

7.Cytotoxic actions of 2,2-dibromo-3-nitrilopropionamide, a biocide in hydraulic fracturing fluids, on rat thymocytes
杀菌剂2,2-二溴-3-次氮基丙酰胺对大鼠胸腺细胞的细胞毒作用
Mizuki Ishikawa, Ryosuke Muraguchi, Ayako Azuma, Shogo Nawata, Mutsumi Miya, Tetsuya Katsuura, Tohru Naito and Yasuo Oyama
Toxicol. Res., 2016, 5, 1329-1334 DOI: 10.1039/C6TX00027D

8.Salvianolic acid B protects against doxorubicin induced cardiac dysfunction via inhibition of ER stress mediated cardiomyocyte apoptosis
丹酚酸B通过抑制ER介导的心肌细胞凋亡拮抗阿霉素诱导的心功能障碍
Rongchang Chen, Guibo Sun, Longpo Yang, Jian Wang and Xiaobo Sun
Toxicol. Res., 2016, 5, 1335-1345 DOI: 10.1039/C6TX00111D

9. In vitro DNA adduct profiling to mechanistically link red meat consumption to colon cancer promotion
体外DNA加合物谱揭示红肉摄入促结肠癌的机制
Lieselot Y. Hemeryck, Caroline Rombouts, Thomas Van Hecke, Lieven Van Meulebroek, Julie Vanden Bussche, Stefaan De Smet and Lynn Vanhaecke
Toxicol. Res., 2016, 5, 1346-1358 DOI: 10.1039/C6TX00079G

10. An in vivo study in mice: mother's gestational exposure to organophosphorus pesticide retards the division and migration process of neural progenitors in the fetal developing brain
母鼠孕期有机磷农药暴露阻碍子代大脑发育中神经前体细胞的分裂与迁移
Xiao-Ping Chen, Ting-Ting Wang, Xiu-Zhong Wu, Da-Wei Wang and Yong-Sheng Chao
Toxicol. Res., 2016, 5, 1359-1370 DOI: 10.1039/C5TX00282

11. Mussel-inspired PEGylated carbon nanotubes: biocompatibility evaluation and drug delivery applications
仿贻贝粘附聚乙二醇修饰碳纳米管的生物相容性评价和药物输送应用
Hui Xu, Meiying Liu, Ming Lan, Huaying Yuan, Weijen Yu, Jianwen Tian, Qing Wan, Xiaoyong Zhang and Yen Wei
Toxicol. Res., 2016, 5, 1371-1379 DOI: 10.1039/C6TX00094

12. Modifications of H3K9me2, H3K36me3 and H4K20me2 may be involved in arsenic-induced genetic damage
H3K9me2, H3K36me3和H4K20me2修饰可能参与砷诱导的遗传损伤过程
Jun Li, Lu Ma, Xilan Wang, Daochuan Li, Qibing Zeng, Xiumei Xing, Chenggui Li, Lang Xie, Li Chen, Wen Chen and Aihua Zhang
Toxicol. Res., 2016, 5, 1380-1387 DOI: 10.1039/C6TX00117C

13. Development of predictive QSAR models for Vibrio fischeri toxicity of ionic liquids and their true external and experimental validation tests
QSAR模型预测离子液体对费氏弧菌毒性的进展及其真实体外验证实验
Rudra Narayan Das, Tânia E. Sintra, João A. P. Coutinho, Sónia P. M. Ventura, Kunal Roy and Paul L. A. Popelier
Toxicol. Res., 2016, 5, 1388-1399 DOI: 10.1039/C6TX00180G

14. Epigenetic disruption and glucose homeostasis changes following low-dose maternal bisphenol A exposure
母体低剂量双酚A暴露导致表观遗传紊乱和血糖稳态改变
Huailong Chang, Danqi Wang, Wei Xia, Xinyun Pan, Wenqian Huo, Shunqing Xu and Yuanyuan Li
Toxicol. Res., 2016, 5, 1400-1409 DOI: 10.1039/C6TX00047A

15. Investigations of the genotoxic properties of two synthetic cathinones (3-MMC, 4-MEC) which are used as psychoactive drugs
两种精神药物-合成卡西酮（3-MMC, 4-MCE）的遗传毒性研究
Halh Al-Serori, Franziska Ferk, Verena Angerer, Miroslav Mišík, Armen Nersesyan, Tahereh Setayesh, Volker Auwärter, Elisabeth Haslinger, Wolfgang Huber and Siegfried Knasmüller
Toxicol. Res., 2016, 5, 1410-1420 DOI: 10.1039/C6TX00087H

16. Oxidative stress and inflammatory responses involved in dietary nickel chloride (NiCl2)-induced pulmonary toxicity in broiler chickens
氧化应激和炎症反应参与氯化镍（NiCl2）诱导的肉鸡肺毒性
Jie Deng, Hongrui Guo, Hengmin Cui, Jing Fang, Zhicai Zuo, Junliang Deng, Xun Wang and Ling Zhao
Toxicol. Res., 2016, 5, 1421-1433 DOI: 10.1039/C6TX00197

17. Proparacaine induces cytotoxicity and mitochondria-dependent apoptosis in corneal stromal cells both in vitro and in vivo
丙美卡因诱导体内外角膜基质细胞的细胞毒性和线粒体依赖的凋亡过程
Wen Yi Fan, Yun Long Sui and Ting Jun Fan
Toxicol. Res., 2016, 5, 1434-1444 DOI: 10.1039/C6TX00286B

18. Lipopolysaccharide attached to urban particulate matter 10 suppresses immune responses in splenocytes while particulate matter itself activates NF-κB
城区PM10颗粒物富集的脂多糖抑制脾细胞免疫应答而颗粒物本身激活NF-κB通路
Yuan Song, Takamichi Ichinose, Miao He, Cuiying He, Kentaro Morita and Yasuhiro Yoshida
Toxicol. Res., 2016, 5, 1445-1452 DOI: 10.1039/C6TX00216A

19. Silica nanoparticles induce start inhibition of meiosis and cell cycle arrest via down-regulating meiotic relevant factors
二氧化硅纳米颗粒通过下调减数分裂相关因子表达抑制减数分裂启动并诱导细胞周期阻滞
Jin Zhang, Lihua Ren, Yang Zou, Lianshuang Zhang, Jialiu Wei, Yanbo Li, Ji Wang, Zhiwei Sun and Xianqing Zhou
Toxicol. Res., 2016, 5, 1453-1464 DOI: 10.1039/C6TX00236F

20. Lead aggravates the diabetic-induced reproductive toxicity in male Wistar rats
铅加剧糖尿病诱导的雄性Wistar大鼠生殖毒性
K. Pratap Reddy, Madamsetti Narayana Rao, J. S. R. Murthy and P. Sreenivasula Reddy
Toxicol. Res., 2016, 5, 1465-1476 DOI: 10.1039/C6TX00099A

21. Fluoride-induced headkidney macrophage cell apoptosis involves activation of the CaMKIIg-ERK 1/2-caspase-8 axis: the role of superoxide in initiating the apoptotic cascade
CaMKIIg-ERK 1/2-caspase-8轴激活参与氟化物诱导的肾巨噬细胞凋亡：超氧化物触发凋亡级联反应的作用
Rashmi Singh, Chaitali Banerjee, Atish Ray, Paulraj Rajamani and Shibnath Mazumder
Toxicol. Res., 2016, 5, 1477-1489 DOI: 10.1039/C6TX00206D